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Artificial Intelligence in Intensive Care Units

Deep Learning-Based Clinical Decisioning Tools

The Challenge
Digitized healthcare data has been growing at a rapid pace, making its productive utilization a challenging endeavor. Clinicians need reliable clinical decision making tools to avert unexpected events that might harm their patients in intensive care units (ICU).

Early prediction of unusual length of stay (LOS) and in-hospital mortality (IHM) for patients in Intensive Care Units (ICU) can help caregivers identify patients at high risk, and effectively manage their care to prevent adverse events.
Approach
01

We utilized Electronic Health Records (EHRs) like chart data, input and output events, laboratory test results, caregiver notes, medications, procedures, imaging reports to build Deep Learning Models (DLMs).

02

Traditional methodologies for building Machine Learning models utilize a curated set of variables,leaving the majority of data unutilized. In contrast, our approach entailed usage of all digitally-captured patient information from EHRs and other sources.

03

Natural Language Processing (NLP) techniques were extensively used to synthesize and combine structured and unstructured datasets.

04

A custom-built deep learning network with input layer, embedding layer, pooling layer, dense layer and output layer was used in the Architecture.

05

Used scalable cloud infrastructure of Google Cloud Platform (GCP) and its tools such as Cloud Storage, Big Query, Tensor Flow, cloud functions and other Artificial Intelligence Platform tools to develop DLMs.

Results

In Hospital Mortality

92% AUC-ROC
60% PR-AUC
67% Balanced Accuracy

Length of Stay

88% AUC-ROC
68% PR-AUC
75% Balanced Accuracy
Conclusion

With this approach, we observed promising model performance from only 42,818 admissions. With a higher volume of patients, more variety of clinical data, and deep learning, one may achieve better model performance.

In this study, we recognized the potential to develop the next generation of clinical practice tools that can augment the efficiency and effectiveness of caregivers in a critical care setting. However, it is only possible when the data is digitized and ready to be used for model development.